PATIENT INFORMATION     How Does It Work?     Treatment Description     Indications

Facts About HBOT > Health Professionals  Hyperbaric Therapy Information - Healthcare Professionals HOW HYPERBARIC OXYGEN THERAPY WORKS Biochemical and Cellular Effects Local hypoxia predisposes wounds to infection because neutrophil mediated killing of bacteria is decreased. Hyperbaric oxygen restores this defense against infection. Local hypoxia leads to poor wound healing.  Adequate tissue oxygen levels are  needed for the formation of the collagen matrix essential for angiogenesis. In irradiated tissue, hyperbaric oxygen offers superior wound healing by these mechanisms. Reperfusion injury can worsen traumatic crush injuries and cause skin flaps and reattachment procedures to fail. Hyperbaric oxygen inhibits the neutrophil adherence and post ischemic vasoconstriction that have been implicated as primary causes of reperfusion injury.      Biological Effects reduction of inert gas bubble size enhanced plasma and tissue oxygenation enhanced neutrophil function stimulation of angiogenesis reactive vascular vasoconstriction inhibition of  membrane lipid peroxidation Jacobi Hyperbaric Chamber Additional Information: Hyperbaric Oxygen Therapy from eMedicine by Michael Neumeister, MD, FRCSC Hyperbaric Oxygen for Acute Carbon Monoxide Poisoning from The New England Journal of Medicine Hyperbaric-Oxygen Therapy (The New England Journal of Medicine, Jun 20, 1996; Tibbles P. M., Edelsberg J. S.) > more Internet resources on Hyperbaric Medicine CONTACT US Physicians and other healthcare professionals interested in hyperbaric oxygen treatment for your patients please contact us.